Opioid drugs are effective painkillers. Made from the opium poppy or synthetically produced, opioids can also make you feel intense pleasure. People who misuse or abuse these drugs can easily become addicted to them. Opioid medications include: codeine, morphine, hydromorphone (Dilaudid®), oxycodone (Percodan®), Fentanyl (Duragesic®), meperidene (Demerol®), pentazocine (Talwin®) and propoxyphene (Darvon®).